Faculty Profile 

Sarah Keating

Contact Information:

Mailing Address:	Mount Sinai Hospital Room 6-500-16 Department of Pathology & Laboratory Medicine 600 University Avenue Toronto, ON M5G 1X5
Phone Number:	416-586-8748
Fax Number:	416-586-8628
Email Address:	skeating@mtsinai.on.ca

Degrees & Professional Designations

• University of Toronto; Masters of Science in Pathology – "The source of lysozyme in articular cartilage."; completed May 1991.
• University of Toronto; 1975-1979; M.D.
• Guelph University; 1973-1975; 5 Semesters of B.Sc. program.
• Fellow of the Royal College of Physicians & Surgeons – Anatomic Pathology

Academic Position: Assistant Professor

Primary Appointment: Department of Laboratory Medicine & Pathobiology

Cross Appointment: Department of Obstetrics & Gynecology

Hospital Affiliations:

• Mount Sinai Hospital, Toronto, Ontario. Staff pathologist – beginning November 1st 2001 – present, Head, Perinatal Pathology Program
• Hospital for Sick Children, Toronto, Ontario – Department of Pathology – Honorary staff

Key Interests:

• Placental pathology & clinical correlates in late unexplained stillbirth – with Dr. John Kingdom & Dr. S. Costa
• Gap junctions and placental vascular remodelling – with Dr. S. Lye, Dr. C. Dunk & Dr. C. Maxwell
• Villous trophoblst turnover in human placenta – with Dr. John Kingdom, Dr. C. Dunk & Dr. J. Cross
• Placental pathology in women with high body mass index – with Dr. C. Maxwell
• Umbilical cord diameter-correlation with fetal outcome – with Dr. W. Whittle & Dr. G. Machin

Grants & Projects:
Intrauterine early & late onset growth retardation and its impact on arterial compliance.
Granting Agency – Heart & Stroke Foundation of Ontario
Principle Investigator – Dr. E. Jaeggi
Co-applicants - J. Kingdom, T. Bradley, S.Keating

Thrombophilia and placental pathology (TAPP).
Granting Agency – Heart & Stroke Foundation of Canada
Principle Investigator – M. Walker & M. Rodger
Co-applicants – S. Keating, J. Kingdom, Q. Yang

Recent Publications:
Fong, K.W, Toi, A., Salem, S., Hornberger, L.K., Chitayat, D., Keating, S.J., McAuliffe, F., Johnson, J-A. Detection of fetal structural abnormalities with US during early pregnancy. Radiographics; (2004) 24:157-174. (C)

Weisberg, L., Kingdom, J., Keating, S., Ryan, G., Seward,G., Kelly, E., Okun, N., Windrim, R. Treatment options in fetomaternal hemorrhage: four case studies. Journal of Obstetrics and Gynecology Canada; (2004) 10:893-8.

Johnson, J.M., Benoit, B., Pierre-Louis, J., Keating, S., Chitayat, D. Occuloauriculofontonasal syndrome (OAFNS): Early prenatal diagnosis of occuloauriculofontonasal syndrome by three-dimensional ultrasound. Ultrasound Obstet. Gynecol. (2004) 2512:184-186.

Finkelstein, Y, Chitayat, D., Schechter, T., Keating, S., Toi, A., Koren, G. Warfarin Embryopathy Following Low Dose Maternal Exposure. Accepted by Obstetrics and Gynecology, Canada Jul; 2005. 27(7): 702-706.

Ellis, C., Pymar, H., Keating, S., Kingdom, J. Non-compaction of the fetal ventricular myocardium presenting with reversed end-diastolic flow velocity in the umbilical arteries. JOGC 2005; 27(7):695-698.

Whittle, W., Keating, S., Al-Sunnar, S., Windrim, R., Okun, N., Kingdom, J. Ischemic-thrombotic placental pathology following second trimester rescue cervical cerclage. In preparation.

Keating, S., Zand, D.J., Shanske, A. Zackai, E.H., Costa, T., Curry, C., Silverman, E., Tiller, G., Unger, S. Miller, S., Chitayat, D. Chondroplasia punctata associated with maternal collagen vascular diseases: Expanding the spectrum from SLE to MCTD and scleroderma. In preparation.

Umranikar, S., Fong, K., Chitayat, D., Keating, S., Glanc, P. X-Linked Dominant Chrondrodysplasia Punctata: Variable Phenotypic Presentation. Accepted with minor revisions.

Slevin, J., Blaser, S., Chitayat, D., Berger, H., Halliday, W., Keating, S., Ryan, G., Toi, A., Pantazi, S., Raybaud, C. “Intraventricular fused fornices”, a marker for complex midline anomalies. Ultrasound in Obstetrics and Gynecology, 2005, 26(4): 311.

McAuliffe, F.M., Fong, K.W., Toi, A., Chitayat, D., Keating, S., Johnson, J.A. Ultrasound detection of fetal anomalies in conjunction with first-trimester nuchal translucency screening: a feasibility study. American Journal of Obstetrics and Gynecology, 2005, 193(3 Pt 2):1260-1265.

Baczyk, D., Dunk, C., Keunen, J., Ansari, T., Huppertz, B., Keating, S., Uxa, R., Perkins, J., Lye, S., Cross, J.C., Kingdom, J. Impaired glial missing-1 medicated trophoblast differentiation in severe intrauterine growth restriction. Sumitted to New England Journal of Medicine, Feb. 2006.

Redline, R.W., Heller, D., Keating, S., Kingdom, J. Placental diagnostic criteria and clinical correlation – A workshop report. Placenta, 2005, 26(Suppl. A):S114-S117.

Toal, M. Chan, C., Fallah S. Keating, S., Machin, G., Windrim, R. Kingdom, J. Abnormal uterine artery Doppler at 18-22 weeks places high-risk women at risk of adverse outcomes from ischemic. Submitted to Placenta.