Dr. Dong’s laboratory investigates steroid receptors in collaborating with RNA splicing factors to control gene transcription and alternative RNA splicing in cells from human reproductive systems. We study how prostate cancer cells can switch off their dependency to androgens and progress into castration resistant cancers. We also study how myometrial cells can develop a functional withdrawal of progesterone at late pregnancy to change the myometrium from a dormant state to the contractile state for parturition.
Dr. Dong received medical school training from China before coming to Canada. He completed an MSc in Molecular and Cellular Biology at Laval University and a PhD in Physiology at the University of Toronto. He received post-doctoral training from the Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto and the Vancouver Prostate Centre, University of British Columbia. He was a recipient of several scholarships for his doctoral and post-doctoral training. He was awarded as a Rising Star by Prostate Cancer Canada.